Altimmune, Inc. ALT
Altimmune, Inc. (Nasdaq: ALT) is a GI/hepatology drug developer. Its lead program, pemvidutide, is in Phase 3 for MASH. Its next catalyst on record is pemvidutide: 52-week PERFORMA Phase 3 readout (2029).
Upcoming catalysts
No catalyst is dated to the next 30 days or to an FDA action date.
Next further out: pemvidutide — 52-week PERFORMA Phase 3 readout (2029). 1 catalyst on record beyond the next 30 days; subscribers see each with its filing sentence.
Pipeline
| Program | Indication | Modality | Stage |
|---|---|---|---|
| pemvidutide | MASH | protein/peptide | Phase 3 |
Recent results and decisions
- Aug 12, 2026started Global PERFORMA Phase 3 MASH trial initiated; 52-week data readout anticipated 2029.
In August 2026, the Company announced the initiation of the global PERFORMA Phase 3 MASH trial, with 52-week data readout anticipated in 2029
Filing - Jul 28, 2026met RECLAIM met primary endpoint: heavy drinking days/week change -4.20 vs -2.75 placebo (diff -1.45, p=0.0014); 2-level WHO-RDL reduction 64.4% vs 34.8% (p=0.0049).
The trial met its primary endpoint with a highly statistically significant reduction in heavy drinking days (HDD) versus placebo
Filing - Dec 19, 2025positive 48-week IMPACT topline: ELF -0.58 (1.8 mg) vs +0.16 placebo, LSM -3.97 kPa vs -0.03 (p<0.0001 / p<0.001), liver fat -54.7% vs -8.2%, weight loss 7.5% vs 0.2%; no serious or severe treatment-related AEs.
Topline 48-week data from the IMPACT trial showed that treatment with pemvidutide achieved statistically significant improvements across treatment arms in key non-invasive tests (NITs), including Enhanced Liver Fibrosis (ELF) and Liver Stiffness Measurement (LSM), versus placebo.
Filing
For subscribers
- Cash runway against each catalyst, with the company's own runway statement
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Other phase 3 GI/hepatology companies
The free Monday brief
Last week's readouts and FDA decisions and the dated catalysts in the week ahead, each with its filing sentence.